This book discusses the organ-specific systemic manifestations of COVID-19. The initial chapters of the book review the origin and evolution of the coronaviruses, followed by pathogenesis and immune response during COVID-19 infection. The book also provides insight into the role of angiotensin-converting enzyme 2 in the onset of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis. It summarizes the neurological aspects of SARS-CoV2, including transmission pathways, mechanisms of invasion into the nervous system, and mechanisms of neurological disease. It also delineates the association of severe disease with high blood plasma levels of inflammatory cytokines and inflammatory markers in SARS-CoV-2 infection. Lastly, it discusses the perturbation of gut microbiota by SARS-CoV-2 and uncovers the potential risk of virus infection on reproductive health.

Chapter1: Corona Viruses: Emergence, Evolution, and Recurrence.- Chapter 2: Testing Strategy of Covid-19: a Mechanistic Approach.- Chapter 3: the Broad Impact of Infectious Disease Epidemics on Human Civilization: a Public Health Perspective.- Chapter 4: Human Impacts on Natural Habitats Leading to Covid-19 Pandemic.- Chapter 5: Transmission of Sars-cov2 and Strategies for Control of Infection - Lessons Learnt.- Chapter 6: Pathogenesis of Covid-19 Infection.- Chapter 7: Pathology of Covid-19 Infection.- Chapter 8: Covid-19: Clinical Spectrum - It's Multiorgan Syndrome.- Chapter 9: Organ Involvement in Covid 19: Lung and Beyond.- Chapter 10: Covid-19 and Mucormycosis.- Chapter 11: Rhino-orbito-cerebral Mucormycosis-the Bane of the 'black Fungus'.- Chapter 12: Strokes, Neurological and Neuropsychiatric Disorders in Covid-19.- Chapter 13: Insights Into Role of Angiotensin-converting Enzyme 2 in the Onset of Severe Acute Respiratory Syndrome Coronavirus 2 Pathogenesis.- Chapter 14: Immunology and Pathogenesis of Covid-19.- Chapter 15: Mrna Vaccine: an Advanced and Transformative Technology for Vaccine Development.- Chapter 16: Dampening of Inflammatory Makers and Understanding Covid 19 Viral Disease Development: a Combinattorial Approach.- Chapter 17: Covid-19: New Use of Therapeutics.- Chapter 18: Pharmacological Agents Targeting Coagulopathy in Covid-19: a Review.- Chapter 19: Gut Microbiome in Covid 19: New Insights'.- Chapter 20: Covid-19 Pandemic and Mental Illness: Impact of Gut-microbiota.- Chapter 21: the Psychological Impact of Covid-19.- Chapter 22: Potential Influence of Parasitic Interactions on Covid-19 Pathology and Epidemiology.- Chapter 23: Plausible Impacts of Sars-cov-2 on Human Reproductive System.- Chapter 24: an Insight Into Association Between Covid-19 Infection and Abo Blood Group.- Chapter 25: Herbal Formulations for the Treatment of Covid-19.- Chapter 26: Covid-19, Nutrition, Immunity and Diet.- Chapter 27: Challenges Faced in Treating Covid-patients and Lessons Learnt.- Chapter 28: Fears, Challenges and Opportunities During Covid 19: a Frontliner's Perspective in Health Care System.