Develop a strong foundation in the concepts and principles of toxicology with this concise and accessible resource
A Doody's Core Title for 2024 & 2023!
For more than 25 years, Casarett & Doull’s Toxicology: The Basics of Poison has set the standard for providing thorough, academic, and authoritative information in clear and engaging ways. Distilling the major principles and concepts from that renowned text, Casarett & Doull’s Essentials of Toxicology delivers an accessible and highly readable introduction to the science and clinical field of medical toxicology. The book reflects the expertise of more than 60 renowned contributors.
Presented in full-color, this new edition builds on the wide success of previous editions, with extensive updates that make the book more clinically relevant to students and beginners in toxicology, pharmacology, pharmacy, and environmental sciences. Chapter-ending self-assessment Q&As and other features make the learning process more effective and efficient.
Casarett and Doull’s Essentials of Toxicology is organized into seven units:
General Principles of ToxicologyDisposition of ToxicantsNon-organ-directed ToxicityTarget Organ ToxicityToxic AgentsEnvironmental ToxicologyApplications of Toxicology
Succinct, yet comprehensive, the text covers essential principles, toxicokinetics, how toxic effects are passed on to succeeding generations, how each body system responds to poisons, and the specific effects of a wide range of toxic agents—from pesticides to radiation.
Preface UNIT 1 GENERAL PRINCIPLES OF TOXICOLOGY 1. The Evolving Journey of Toxicology: A Historical Glimpse 2. Principles of Toxicology 3. Mechanisms of Toxicity 4. Risk Assessment UNIT 2 DISPOSITION OF TOXICANTS 5. Absorption, Distribution, and Excretion of Toxicants 6. Biotransformation of Xenobiotics 7. Toxicokinetics UNIT 3 NON-ORGAN-DIRECTED TOXICITY 8. Chemical Carcinogenesis 9. Genetic Toxicology 10. Developmental Toxicology UNIT 4 TARGET ORGAN TOXICITY 11. Toxic Responses of the Blood 12. Toxic Responses of the Immune System 13. Toxic Responses of the Liver 14. Toxic Responses of the Kidney 15. Toxic Responses of the Respiratory System 16. Toxic Responses of the Nervous System 17. Toxic Responses of the Cornea, Retina, and Central Visual System 18. Toxic Responses of the Heart and Vascular System 19. Toxic Responses of the Skin 20. Toxic Responses of the Endocrine System 21. Toxic Responses of the Reproductive System UNIT 5 TOXIC AGENTS 22. Toxic Effects of Pesticides 23. Toxic Effects of Metals 24. Toxic Effects of Solvents and Vapors 25. Toxic Effects of Radiation and Radioactive Materials 26. Toxic Effects of Plants and Animals 27. Food Toxicology: Fundamental and Regulatory Aspects 28. Toxic Effects of Calories 29. Nanoparticle Toxicology UNIT 6 ENVIRONMENTAL TOXICOLOGY 30. Ecotoxicology 31. Air Pollution UNIT 7 APPLICATIONS OF TOXICOLOGY 32. Analytical and Forensic Toxicology 33. Clinical Toxicology 34. Occupational Toxicology Answers to Chapter Questions Index